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Contraindicated (one)pentobarbital will lower the extent or outcome of roflumilast by impacting hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital will reduce the extent or impact of methadone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.RETURN, Substitution AND REFUND Coverage: If we created a blunder througho